{"id":2394,"date":"2026-05-22T07:00:02","date_gmt":"2026-05-22T07:00:02","guid":{"rendered":"https:\/\/www.thefullerene.com\/?p=2394"},"modified":"2026-05-22T07:05:25","modified_gmt":"2026-05-22T07:05:25","slug":"catalyst-poisoning-metal-free-fullerene-precursors","status":"publish","type":"post","link":"https:\/\/www.thefullerene.com\/ko\/catalyst-poisoning-metal-free-fullerene-precursors\/","title":{"rendered":"\ud480\ub7ec\ub80c\uc774 \uba5c\ub77c\ub2cc \ud569\uc131\uc744 \uc870\uc808\ud558\uace0 \uc790\uc678\uc120 \uc190\uc0c1\uc73c\ub85c\ubd80\ud130 \ubc29\uc5b4\ud558\ub294 \ubc29\ubc95: \ud53c\ubd80 \uad11\ubcf4\ud638\uc5d0 \ub300\ud55c \ubd84\uc790\uc801 \ubd84\uc11d"},"content":{"rendered":"<p class=\"wp-block-paragraph\">\ud53c\ubd80 \uc778\ud130\ud398\uc774\uc2a4\ub294 \uc9c0\uc18d\uc801\uc73c\ub85c \ud0dc\uc591 \uc790\uc678\uc120(Ultraviolet Radiation, UVR)\uc5d0 \ub178\ucd9c\ub418\uba70, \uc774\ub294 UVB(290\u2013320 nm)\uc640 UVA(320\u2013400 nm) \ud30c\uc7a5\uc73c\ub85c \uad6c\ubd84\ub429\ub2c8\ub2e4. UVB\ub294 \uc8fc\ub85c \ud45c\ud53c\ub97c \ud45c\uc801\uc73c\ub85c \ud558\uc5ec \uc9c1\uc811\uc801\uc778 DNA \uc190\uc0c1\uc744 \uc720\ubc1c\ud558\ub294 \ubc18\uba74, UVA\ub294 \uc9c4\ud53c \uae4a\uc219\uc774 \uce68\ud22c\ud558\uc5ec \uacfc\ub3c4\ud55c \ud65c\uc131\uc0b0\uc18c\uc885(Reactive Oxygen Species, ROS)\uc744 \uc0dd\uc131\ud569\ub2c8\ub2e4. \uc774\ub807\uac8c UV\uc5d0 \uc758\ud574 \uc720\ubc1c\ub41c \uc0b0\ud654 \uc2a4\ud2b8\ub808\uc2a4\ub294 \uc870\uae30 \ub178\ud654(\uad11\ub178\ud654) \ubc0f \uae30\ubbf8, \uc8fc\uadfc\uae68, \uc77c\uad11 \ud751\uc790 \ub4f1\uc744 \ud3ec\ud568\ud55c \uc0c9\uc18c\uce68\ucc29 \uc7a5\uc560\uc758 \uc8fc\uc694 \uc0c1\uc704 \uc720\ubc1c \uc694\uc778\uc785\ub2c8\ub2e4.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\uc774\ub7ec\ud55c \uc190\uc0c1\uc744 \ubc29\uc9c0\ud558\uae30 \uc704\ud574, \ud604\ub300 \ud53c\ubd80\uacfc\ud559 \uc5f0\uad6c\ub294 \ub6f0\uc5b4\ub09c \ud56d\uc0b0\ud654 \ub2a5\ub825\uc744 \uc9c0\ub2cc \ub098\ub178\ubb3c\uc9c8\uc5d0 \ucd08\uc810\uc744 \ub9de\ucd94\uace0 \uc788\uc2b5\ub2c8\ub2e4. \uadf8\uc911\uc5d0\uc11c\ub3c4 \uce74\ubcf8 60(<a href=\"https:\/\/www.thefullerene.com\/about-fullerene\/what-is-fullerene-c60\/\">C60<\/a>) \ud480\ub7ec\ub80c\u2014\uc815\uc774\uc2ed\uba74\uccb4 \ub300\uce6d\uc744 \uac00\uc9c4 \uc18d\uc774 \ube48 \uad6c\ud615 \ucf00\uc774\uc9c0\u2014\ub294 \ucd5c\uace0\uc758 \ud65c\uc131 \uc131\ubd84\uc73c\ub85c \ubd80\uc0c1\ud588\uc2b5\ub2c8\ub2e4. \u201c\ub77c\ub514\uce7c \uc2a4\ud380\uc9c0\u201d \uc5ed\ud560\uc744 \ud558\uba70,\u201d <a href=\"https:\/\/www.thefullerene.com\/about-fullerene\/what-is-fullerene-c60\/\">C60<\/a> \ucd09\ub9e4 \ud6a8\uc728\ub85c \uc790\uc720 \ub77c\ub514\uce7c\uc744 \uc911\ud654\uc2dc\ucf1c \uae30\uc874 \ud56d\uc0b0\ud654\uc81c\uc758 \uc131\ub2a5\uc744 \ud6e8\uc52c \ub2a5\uac00\ud569\ub2c8\ub2e4. \ubcf8 \ub17c\ubb38\uc740 \ud480\ub7ec\ub80c\uc774 \uba5c\ub77c\ub2cc \uc0dd\uc131\uc744 \uc870\uc808\ud558\uace0 \uc790\uc678\uc120 \uc720\uc804\ub3c5\uc131\uc73c\ub85c\ubd80\ud130 \uc778\uac04 \ud53c\ubd80\ub97c \ubcf4\ud638\ud558\ub294 \ubd84\uc790 \uba54\ucee4\ub2c8\uc998\uc5d0 \ub300\ud55c \ud3ec\uad04\uc801\uc778 \uac80\ud1a0\ub97c \uc81c\uacf5\ud569\ub2c8\ub2e4.<\/p>\n\n\n\n<div class=\"wp-block-rank-math-toc-block\" id=\"rank-math-toc\"><h2>\ubaa9\ucc28<\/h2><nav><ul><li><a href=\"#1-the-melanogenesis-pathway-and-oxidative-triggers\">1. \uba5c\ub77c\ub2cc \uc0dd\uc131 \uacbd\ub85c \ubc0f \uc0b0\ud654\uc801 \uc720\ubc1c \uc694\uc778<\/a><\/li><li><a href=\"#undefined-1\">2. Molecular Inhibition of Melanin Synthesis by C60<\/a><ul><li><a href=\"#undefined-2\">\uc0c1\ub958 ROS \uc18c\uac70<\/a><\/li><li><a href=\"#undefined-3\">\uc8fc\uc694 \uba5c\ub77c\ub2cc \uc0dd\uc131 \uc720\uc804\uc790\uc758 \ud558\ud5a5 \uc870\uc808<\/a><\/li><\/ul><\/li><li><a href=\"#3-photoprotection-and-prevention-of-uv-induced-genotoxicity\">3. \uad11\ubcf4\ud638 \ubc0f \uc790\uc678\uc120 \uc720\uc804\ub3c5\uc131 \uc608\ubc29<\/a><ul><li><a href=\"#prevention-of-dna-damage-and-apoptosis\">DNA \uc190\uc0c1 \ubc0f \uc138\ud3ec\uc0ac\uba78 \uc608\ubc29<\/a><\/li><li><a href=\"#inhibition-of-lipid-peroxidation\">\uc9c0\uc9c8 \uacfc\uc0b0\ud654 \uc5b5\uc81c<\/a><\/li><\/ul><\/li><li><a href=\"#4-cosmetic-synthesis-and-purity-standards\">4. \ud654\uc7a5\ud488 \ud569\uc131 \ubc0f \uc21c\ub3c4 \uae30\uc900<\/a><\/li><li><a href=\"#faq\">FAQ<\/a><ul><li><a href=\"#how-does-c60-fullerene-differ-from-vitamin-c-as-a-skin-brightening-active\">C60 \ud480\ub7ec\ub80c\uc740 \ud53c\ubd80 \ubbf8\ubc31 \ud65c\uc131 \uc131\ubd84\uc73c\ub85c\uc11c \ube44\ud0c0\ubbfc C\uc640 \uc5b4\ub5bb\uac8c \ub2e4\ub978\uac00\uc694?<\/a><\/li><li><a href=\"#can-fullerenes-be-formulated-in-both-water-based-and-oil-based-cosmetics\">\ud480\ub7ec\ub80c\uc740 \uc218\uc131 \ubc0f \uc720\uc131 \ud654\uc7a5\ud488 \ubaa8\ub450\uc5d0 \ubc30\ud569\ub420 \uc218 \uc788\uc2b5\ub2c8\uae4c?<\/a><\/li><li><a href=\"#does-c60-provide-actual-spf-protection-like-physical-sunscreens\">C60\uc774 \ubb3c\ub9ac\uc801 \uc790\uc678\uc120 \ucc28\ub2e8\uc81c\uc640 \uac19\uc740 \uc2e4\uc81c SPF \ubcf4\ud638 \uae30\ub2a5\uc744 \uc81c\uacf5\ud569\ub2c8\uae4c?<\/a><\/li><li><a href=\"#how-does-c60-prevent-uv-induced-dna-damage-in-skin-cells\">C60\uc774 \ud53c\ubd80 \uc138\ud3ec\uc5d0\uc11c \uc790\uc678\uc120 \uc720\ubc1c DNA \uc190\uc0c1\uc744 \uc5b4\ub5bb\uac8c \uc608\ubc29\ud569\ub2c8\uae4c?<\/a><\/li><li><a href=\"#are-there-any-side-effects-or-risks-associated-with-topical-c60\">\uad6d\uc18c\uc6a9 C60\uacfc \uad00\ub828\ub41c \ubd80\uc791\uc6a9\uc774\ub098 \uc704\ud5d8\uc774 \uc788\uc2b5\ub2c8\uae4c?<\/a><\/li><\/ul><\/li><li><a href=\"#references\">\ucc38\uace0\ubb38\ud5cc<\/a><\/li><\/ul><\/nav><\/div>\n\n\n\n<h2 id=\"1-the-melanogenesis-pathway-and-oxidative-triggers\" class=\"wp-block-heading\">1. \uba5c\ub77c\ub2cc \uc0dd\uc131 \uacbd\ub85c \ubc0f \uc0b0\ud654\uc801 \uc720\ubc1c \uc694\uc778<\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">\uba5c\ub77c\ub2cc \uc0dd\uc131\uc740 \ud45c\ud53c \uba5c\ub77c\ub2cc\uc138\ud3ec \ub0b4\ubd80\uc5d0 \uc704\uce58\ud55c \uba5c\ub77c\ub178\uc19c\uc774\ub77c\ub294 \ud2b9\uc218\ud55c \ub9ac\uc18c\uc880 \uc720\uc0ac \uc18c\uae30\uad00 \ub0b4\uc5d0\uc11c \ubc1c\uc0dd\ud558\ub294 \uace0\ub3c4\ub85c \uc870\uc808\ub41c \uc0dd\ud654\ud559\uc801 \uacbd\ub85c\uc785\ub2c8\ub2e4. \uc774 \uacbd\ub85c\uc758 \uae30\ubcf8\uc801\uc774\uba74\uc11c \uc18d\ub3c4 \uc81c\ud55c \ub2e8\uacc4\ub294 \uad6c\ub9ac \ud568\uc720 \uae08\uc18d\ud6a8\uc18c\uc778 \ud2f0\ub85c\uc2dc\ub098\uc81c(EC 1.14.18.1)\uc5d0 \uc758\ud574 \uc870\uc808\ub429\ub2c8\ub2e4. <a href=\"https:\/\/en.wikipedia.org\/wiki\/Tyrosinase\" data-type=\"link\" data-id=\"https:\/\/en.wikipedia.org\/wiki\/Tyrosinase\" rel=\"nofollow noopener\" target=\"_blank\">\ud2f0\ub85c\uc2dc\ub098\uc81c\ub294<\/a> \ub450 \uac00\uc9c0 \uc21c\ucc28\uc801\uc774\uace0 \uad6c\ubcc4\ub418\ub294 \ubc18\uc751\uc744 \uc870\uc815\ud569\ub2c8\ub2e4:<\/p>\n\n\n\n<ol start=\"1\" class=\"wp-block-list\">\n<li>L-\ud2f0\ub85c\uc2e0\uc744 L-3,4-\ub514\ud788\ub4dc\ub85d\uc2dc\ud398\ub2d0\uc54c\ub77c\ub2cc(L-DOPA)\uc73c\ub85c \uc218\uc0b0\ud654\ud558\ub294 \ubaa8\ub178\ud398\ub180\ub77c\uc81c \uc0ac\uc774\ud074.<\/li>\n\n\n\n<li>L-DOPA\ub97c \ubc18\uc751\uc131\uc774 \ub192\uc740 o-\ub3c4\ud30c\ud034\ub17c\uc73c\ub85c \uc0b0\ud654\uc2dc\ud0a4\ub294 \ub514\ud398\ub180\ub77c\uc81c \uc0ac\uc774\ud074.<\/li>\n<\/ol>\n\n\n\n<p class=\"wp-block-paragraph\">\uc124\ud504\ud788\ub4dc\ub9b4 \ud654\ud569\ubb3c(\uc608: \uae00\ub8e8\ud0c0\ud2f0\uc628 \ub610\ub294 \uc2dc\uc2a4\ud14c\uc778)\uc774 \uc5c6\ub294 \uacbd\uc6b0, o-\ub3c4\ud30c\ud034\ub17c\uc740 \uc2e0\uc18d\ud558\uac8c <a href=\"https:\/\/pubs.acs.org\/doi\/10.1021\/acs.chemrev.2c00306\" data-type=\"link\" data-id=\"https:\/\/pubs.acs.org\/doi\/10.1021\/acs.chemrev.2c00306\" rel=\"nofollow noopener\" target=\"_blank\">\ube44\ud6a8\uc18c\uc801 \uace0\ub9ac\ud654 \ubc18\uc751<\/a> \uc744 \uac70\uccd0 \ub3c4\ud30c\ud06c\ub86c\uc744 \ud615\uc131\ud569\ub2c8\ub2e4. \uc774 \uc911\uac04\uccb4\ub294 \uc774\ud6c4 \ud2f0\ub85c\uc2dc\ub098\uc81c \uad00\ub828 \ub2e8\ubc31\uc9c8 1(TRP-1) \ubc0f \ud2f0\ub85c\uc2dc\ub098\uc81c \uad00\ub828 \ub2e8\ubc31\uc9c8 2(TRP-2)\uc5d0 \uc758\ud574 \ucd09\ub9e4\ub418\uc5b4 \ubd88\uc6a9\uc131\uc758 \ud751\uac08\uc0c9 \uc0c9\uc18c\uc778 \uc720\uba5c\ub77c\ub2cc\uc744 \uc0dd\uc131\ud569\ub2c8\ub2e4.<\/p>\n\n\n\n<figure class=\"wp-block-image aligncenter size-large\"><img loading=\"lazy\" decoding=\"async\" width=\"1024\" height=\"686\" src=\"https:\/\/www.thefullerene.com\/wp-content\/uploads\/2026\/05\/42003_2025_8725_fig1_html-1024x686.webp\" alt=\"\" class=\"wp-image-2400\" title=\"\" srcset=\"https:\/\/www.thefullerene.com\/wp-content\/uploads\/2026\/05\/42003_2025_8725_fig1_html-1024x686.webp 1024w, https:\/\/www.thefullerene.com\/wp-content\/uploads\/2026\/05\/42003_2025_8725_fig1_html-720x482.webp 720w, https:\/\/www.thefullerene.com\/wp-content\/uploads\/2026\/05\/42003_2025_8725_fig1_html-300x201.webp 300w, https:\/\/www.thefullerene.com\/wp-content\/uploads\/2026\/05\/42003_2025_8725_fig1_html-768x515.webp 768w, https:\/\/www.thefullerene.com\/wp-content\/uploads\/2026\/05\/42003_2025_8725_fig1_html-1536x1029.webp 1536w, https:\/\/www.thefullerene.com\/wp-content\/uploads\/2026\/05\/42003_2025_8725_fig1_html-18x12.webp 18w, https:\/\/www.thefullerene.com\/wp-content\/uploads\/2026\/05\/42003_2025_8725_fig1_html.webp 2000w\" sizes=\"auto, (max-width: 1024px) 100vw, 1024px\" \/><figcaption class=\"wp-element-caption\">\ub2e4\uc591\ud55c \uc720\ud615\uc758 \uc790\uc678\uc120\uc774 \uc138\ud3ec \ub0b4\ub85c \uce68\ud22c\ud558\ub294 \uae4a\uc774, \ub2e4\uc591\ud55c \ud53c\ubd80\uce35 \uc0dd\uc131, \ubc0f \uc774 \ubc29\uc0ac\uc120\uc73c\ub85c \uc778\ud55c \uc138\ud3ec \uae30\ub2a5\uc758 \uc8fc\uc694 \ubcc0\ud654<\/figcaption><\/figure>\n\n\n\n<p class=\"wp-block-paragraph\">\ud2f0\ub85c\uc2dc\ub098\uc81c, TRP-1 \ubc0f TRP-2\ub97c \ucf54\ub529\ud558\ub294 \uc720\uc804\uc790\uc758 \uc804\uc0ac\ub294 \ub9c8\uc2a4\ud130 \uc870\uc808\uc790\uc774\uc790 \ubbf8\uc138\uc548\uad6c\uc5f0\uad00\uc804\uc0ac\uc778\uc790(Microphthalmia-associated Transcription Factor, MITF)\uc5d0 \uc758\ud574 \uc870\uc815\ub429\ub2c8\ub2e4. UV\uc5d0 \ub178\ucd9c\ub418\uba74 \uac01\uc9c8\ud615\uc131\uc138\ud3ec\ub294 \uc54c\ud30c-\uba5c\ub77c\ub2cc\uc138\ud3ec\uc790\uadf9\ud638\ub974\ubaac(\u03b1-MSH)\uc744 \ubc29\ucd9c\ud558\uba70, \uc774\ub294 \uba5c\ub77c\ub2cc\uc138\ud3ec\uc758 \uba5c\ub77c\ub178\ucf54\ub974\ud2f4-1 \uc218\uc6a9\uccb4(MC1R)\uc5d0 \uacb0\ud569\ud558\uc5ec cAMP\/\ub2e8\ubc31\uc9c8 \ud0a4\ub098\uc544\uc81c A(PKA) \uc2e0\ud638\uc804\ub2ec\uc744 \ucd09\ubc1c\ud558\uc5ec MITF\ub97c \uc0c1\ud5a5 \uc870\uc808\ud569\ub2c8\ub2e4.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\ub3d9\uc2dc\uc5d0, UV \uc720\ubc1c ROS\ub294 \uac15\ub825\ud55c 2\ucc28 \uc804\ub2ec\uc790 \uc5ed\ud560\uc744 \ud569\ub2c8\ub2e4. \uc774 \uc790\uc720 \ub77c\ub514\uce7c\uc740 p38 \ubbf8\ud1a0\uac90 \ud65c\uc131\ud654 \ub2e8\ubc31\uc9c8 \ud0a4\ub098\uc544\uc81c(MAPK) \uacbd\ub85c\ub97c \ud65c\uc131\ud654\uc2dc\ud0a4\uba70, \uc774 \uacbd\ub85c\ub294 \uc9c1\uc811\uc801\uc73c\ub85c <a href=\"https:\/\/medlineplus.gov\/download\/genetics\/gene\/mitf.pdf\" data-type=\"link\" data-id=\"https:\/\/medlineplus.gov\/download\/genetics\/gene\/mitf.pdf\" rel=\"nofollow noopener\" target=\"_blank\">MITF<\/a>, \ub97c \uc778\uc0b0\ud654\ud558\uace0 \ud65c\uc131\ud654\ud558\uc5ec \ud2f0\ub85c\uc2dc\ub098\uc81c \ubc1c\ud604\uc758 \uae09\uaca9\ud55c \uc99d\uac00\ub97c \uc720\ubc1c\ud558\uace0 \uac00\uc2dc\uc801\uc778 \uc0c9\uc18c\uce68\ucc29\uc744 \ucd08\ub798\ud569\ub2c8\ub2e4.<\/p>\n\n\n\n<h2 id=\"undefined-1\" class=\"wp-block-heading\">2. \uba5c\ub77c\ub2cc \ud569\uc131\uc758 \ubd84\uc790\uc801 \uc5b5\uc81c <a href=\"https:\/\/www.thefullerene.com\/about-fullerene\/what-is-fullerene-c60\/\">C60<\/a><\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">\ud480\ub7ec\ub80c C60\uc740 \uc8fc\ub85c \uc0c9\uc18c\uce68\ucc29\uc758 \uc804\uc0ac \uae30\uc804\uc744 \ucd09\ubc1c\ud558\uae30 \uc804\uc5d0 \uc0c1\uc704 \uc0b0\ud654 \uc2e0\ud638\ub97c \ucc28\ub2e8\ud568\uc73c\ub85c\uc368 \uc0c9\uc18c\uce68\ucc29\uc744 \uc870\uc808\ud569\ub2c8\ub2e4.<\/p>\n\n\n\n<h3 id=\"undefined-2\" class=\"wp-block-heading\">\uc0c1\ub958 ROS \uc18c\uac70<\/h3>\n\n\n\n<p class=\"wp-block-paragraph\">\uc218\uc6a9\uc131 \uace0\ubd84\uc790 \ub7a9\ud551 \uc720\ub3c4\uccb4(\uc77c\ubc18\uc801\uc73c\ub85c \ud3f4\ub9ac\ube44\ub2d0\ud53c\ub864\ub9ac\ub3c8(PVP)\uc73c\ub85c \uc548\uc815\ud654\ub418\uba70 \u201c\ub77c\ub514\uce7c \uc2a4\ud380\uc9c0\u201d\ub85c \uc54c\ub824\uc9d0)\ub85c \uc81c\ud615\ud654\ub420 \ub54c, C60\uc740 <a href=\"https:\/\/starwars.fandom.com\/wiki\/Molecular_shielding\" rel=\"nofollow noopener\" target=\"_blank\">\ubd84\uc790 \ubcf4\ud638\ub9c9<\/a>. \uc5ed\ud560\uc744 \ud569\ub2c8\ub2e4. UVA \uc870\uc0ac \uc2dc, \uba5c\ub77c\ub2cc\uc138\ud3ec \ub0b4\ubd80\uc758 \ud480\ub7ec\ub80c\uc740 \uc2e0\uc18d\ud558\uac8c \ud65c\uc131\uc885\uc744 \ud761\uc218\ud558\uace0 \uc18c\uad11\uc2dc\ucf1c \uc0b0\ud654\uc801 \uc720\ubc1c \uc694\uc778\uc744 \uc81c\uac70\ud569\ub2c8\ub2e4. \uc804\ub958\uce21\uc815\ubc95 \ubc0f \ud615\uad11\uce21\uc815\ubc95 \ubd84\uc11d\uc740 \uc774\ub7ec\ud55c \uc9c0\uc18d\uc801\uc778 \ub77c\ub514\uce7c \uc18c\uac70 \uc791\uc6a9\uc774 p38 MAPK \uce90\uc2a4\ucf00\uc774\ub4dc\uc758 \ud65c\uc131\ud654\ub97c \uc911\ub2e8\uc2dc\ud0a8\ub2e4\ub294 \uac83\uc744 \ud655\uc778\ud569\ub2c8\ub2e4.<\/p>\n\n\n\n<h3 id=\"undefined-3\" class=\"wp-block-heading\">\uc8fc\uc694 \uba5c\ub77c\ub2cc \uc0dd\uc131 \uc720\uc804\uc790\uc758 \ud558\ud5a5 \uc870\uc808<\/h3>\n\n\n\n<p class=\"wp-block-paragraph\">ROS \ub9e4\uac1c MITF \ud65c\uc131\ud654\ub97c \ucc28\ub2e8\ud568\uc73c\ub85c\uc368, C60\uc740 \uc804\uccb4 \uba5c\ub77c\ub2cc \uc0dd\uc131 \ub2e4\uc911\ud6a8\uc18c \ubcf5\ud569\uccb4\uc758 \ud558\uc704 \ubc1c\ud604\uc744 \uc5b5\uc81c\ud569\ub2c8\ub2e4. \uc5f0\uad6c\uc5d0 \ub530\ub974\uba74 C60 \ucc98\ub9ac\ub294 \ub2e4\uc74c\uc744 \uc720\uc758\ubbf8\ud558\uac8c \ud558\ud5a5 \uc870\uc808\ud569\ub2c8\ub2e4:<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>MITF<\/strong> \uc720\uc804\uc790 \ubc0f \ub2e8\ubc31\uc9c8 \ubc1c\ud604.<\/li>\n\n\n\n<li><strong>\ud2f0\ub85c\uc2dc\ub098\uc81c\ub294<\/strong> \ud6a8\uc18c \ud65c\uc131 \ubc0f \ucd1d \ub2e8\ubc31\uc9c8 \uc218\uc900.<\/li>\n\n\n\n<li><strong>TRP-1 \ubc0f TRP-2<\/strong> \uc804\uc0ac, \uba5c\ub77c\ub178\uc19c \uc131\uc219\uc744 \ubc29\uc9c0\ud569\ub2c8\ub2e4.<\/li>\n<\/ul>\n\n\n\n<p class=\"wp-block-paragraph\">\ub610\ud55c, \ud480\ub7ec\ub80c\uc740 UVB \ub178\ucd9c \ud6c4 \uc7ac\uad6c\uc131\ub41c \uc778\uccb4 \ud45c\ud53c(RhE)\uc5d0\uc11c \ud504\ub85c\uc2a4\ud0c0\uae00\ub780\ub518 E2(PGE2)\uc758 \ud569\uc131\uc744 \uc5b5\uc81c\ud569\ub2c8\ub2e4. PGE2\ub294 <a href=\"https:\/\/en.wikipedia.org\/wiki\/Paracrine_signaling\" rel=\"nofollow noopener\" target=\"_blank\">\uce21\ubd84\ube44 \uc790\uadf9\uc778\uc790<\/a> \ub85c \uc791\uc6a9\ud558\uc5ec \ud2f0\ub85c\uc2dc\ub098\uc81c \ud65c\uc131\uc744 \uc99d\uac00\uc2dc\ud0a4\uace0 \uba5c\ub77c\ub2cc\uc138\ud3ec\uc758 \uc218\uc9c0\uc0c1 \ub3cc\uae30 \ud615\uc131\uc744 \ucd09\uc9c4\ud558\uc5ec(\uc131\uc219\ud55c \uba5c\ub77c\ub178\uc19c\uc744 \uac01\uc9c8\ud615\uc131\uc138\ud3ec\ub85c \uc804\ub2ec\ud560 \uc218 \uc788\uac8c \ud568) \ud53c\ubd80 \ud0dc\ub2dd \ubc0f \ubc18\uc810 \ud615\uc131\uc744 \ubc29\uc9c0\ud558\ub294 \uac15\ub825\ud55c 2\ucc28 \uba54\ucee4\ub2c8\uc998\uc73c\ub85c \uc791\uc6a9\ud569\ub2c8\ub2e4.<\/p>\n\n\n\n<h2 id=\"3-photoprotection-and-prevention-of-uv-induced-genotoxicity\" class=\"wp-block-heading\">3. \uad11\ubcf4\ud638 \ubc0f \uc790\uc678\uc120 \uc720\uc804\ub3c5\uc131 \uc608\ubc29<\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">\uc804\ud1b5\uc801\uc778 \ubbf8\ubc31 \ud65c\uc131 \uc131\ubd84\uc740 \ud6a8\uc18c \uacbd\ub85c\uc5d0\ub9cc \ucd08\uc810\uc744 \ub9de\ucd94\ub294 \ubc18\uba74, C60\uc740 \ubb3c\ub9ac\uc801 UV \uc190\uc0c1 \ubc0f \uc720\uc804\ub3c5\uc131\uc73c\ub85c\ubd80\ud130 \ud45c\ud53c \uc138\ud3ec\ub97c \ubcf4\ud638\ud558\uc5ec \uad11\ubc94\uc704\ud55c \ubcf4\ud638 \uae30\ub2a5\uc744 \uc81c\uacf5\ud569\ub2c8\ub2e4.<\/p>\n\n\n\n<h3 id=\"prevention-of-dna-damage-and-apoptosis\" class=\"wp-block-heading\">DNA \uc190\uc0c1 \ubc0f \uc138\ud3ec\uc0ac\uba78 \uc608\ubc29<\/h3>\n\n\n\n<p class=\"wp-block-paragraph\">\ucd08\uace0\uc218\uc0b0\ud654 \ud480\ub7ec\ub80c \uc720\ub3c4\uccb4, \uc989 <a href=\"https:\/\/www.researchgate.net\/publication\/47366690_Fullerenol_A_new_nanopharmaceutic\" rel=\"nofollow noopener\" target=\"_blank\">\ud480\ub7ec\ub808\ub180<\/a> (\uc608: C60(OH)44)\uc740 \ud0c1\uc6d4\ud55c \uc218\uc6a9\uc131\uacfc \uc0dd\uccb4\uc801\ud569\uc131\uc744 \uac00\uc9c0\uace0 \uc788\uc2b5\ub2c8\ub2e4. \uc778\uac04 \uac01\uc9c8\ud615\uc131\uc138\ud3ec(HaCaT)\uc5d0\uc11c \ud480\ub7ec\ub808\ub180\ub85c \uc804\ucc98\ub9ac\ud558\uba74 UVB \uad11\uc120\uc5d0 \uc758\ud574 \uc720\ub3c4\ub41c \uc138\ud3ec\uc790\uba78\uc0ac\uac00 \uc720\uc758\ubbf8\ud558\uac8c \uc5b5\uc81c\ub429\ub2c8\ub2e4.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\ubd84\uc790 \uc218\uc900\uc5d0\uc11c \ud480\ub7ec\ub808\ub180\uc740 \uc138\ud3ec \ud575\uc744 \uacf5\uaca9\ud558\ub294 \uc218\uc0b0\uae30 \ub77c\ub514\uce7c(\u2022OH)\uc744 \uc911\ud654\uc2dc\ucf1c \uc5fc\uc0c9\uc9c8 \uc751\ucd95\uc744 \ud68d\uae30\uc801\uc73c\ub85c \uc904\uc774\uace0 \ud53c\ubd80 \ubc1c\uc554\uc758 \uc8fc\uc694 \uc720\uc804\uc801 \ub3cc\uc5f0\ubcc0\uc774\uc778 \uc0ac\uc774\ud074\ub85c\ubd80\ud0c4 \ud53c\ub9ac\ubbf8\ub518 \uc774\ub7c9\uccb4(CPD)\uc758 \ud615\uc131\uc744 \uc5b5\uc81c\ud569\ub2c8\ub2e4.<\/p>\n\n\n\n<h3 id=\"inhibition-of-lipid-peroxidation\" class=\"wp-block-heading\">\uc9c0\uc9c8 \uacfc\uc0b0\ud654 \uc5b5\uc81c<\/h3>\n\n\n\n<p class=\"wp-block-paragraph\">\ud53c\uc9c0, \ud2b9\ud788 <a href=\"https:\/\/en.wikipedia.org\/wiki\/Squalene\" rel=\"nofollow noopener\" target=\"_blank\">\uc2a4\ucfe0\uc54c\ub80c<\/a>, \uc740 UVB \uc720\ubc1c \uacfc\uc0b0\ud654\uc5d0 \ub9e4\uc6b0 \ucde8\uc57d\ud558\uc5ec \ud53c\ubd80 \uc7a5\ubcbd\uc744 \uc190\uc0c1\uc2dc\ud0a4\uace0 \uc5ec\ub4dc\ub984\uc744 \uc545\ud654\uc2dc\ud0a4\ub294 \uc5fc\uc99d\uc131 \ubd80\uc0b0\ubb3c\uc744 \uc0dd\uc131\ud569\ub2c8\ub2e4. \uce5c\uc720\uc131 C60\uc740 \uc2dd\ubb3c \uc720\ub798 \uc2a4\ucfe0\uc54c\ub780(\uc608: \ub9ac\ud3ec\ud480\ub7ec\ub80c)\uc5d0 \uc6a9\ud574\ub420 \ub54c \uac01\uc9c8\uce35 \ubc0f \ud53c\uc9c0\uc120\uc758 \uc9c0\uc9c8 \uc774\uc911\uce35\uc5d0 \uc27d\uac8c \ud1b5\ud569\ub429\ub2c8\ub2e4.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">UVB \uc870\uc0ac \ud558\uc5d0\uc11c \uce5c\uc720\uc131 C60\uc740 \uc2a4\ucfe0\uc54c\ub80c\uc758 \uc0b0\ud654\uc801 \ubd84\ud574\ub97c \ubc29\uc9c0\ud558\uc5ec \ub9c9 \uc720\ub3d9\uc131\uc744 \uc720\uc9c0\ud558\uace0, \ud53c\ubd80 \ud64d\ubc18\uc744 \uac10\uc18c\uc2dc\ud0a4\uba70, \uc790\uc5f0\uc801\uc778 \uc7a5\ubcbd \uae30\ub2a5\uc744 \ubc29\ud574\ud558\uc9c0 \uc54a\uc73c\uba74\uc11c \uc5fc\uc99d\uc131 \uc5ec\ub4dc\ub984 \ubcd1\ubcc0\uc744 \ub0ae\ucda5\ub2c8\ub2e4.<\/p>\n\n\n\n<h2 id=\"4-cosmetic-synthesis-and-purity-standards\" class=\"wp-block-heading\">4. \ud654\uc7a5\ud488 \ud569\uc131 \ubc0f \uc21c\ub3c4 \uae30\uc900<\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">\uace0\uae09 \uc2a4\ud0a8\ucf00\uc5b4 \uc81c\ud615\uc5d0\uc11c C60\uc758 \ud6a8\ub2a5\uc740 \ubd84\uc790 \uc21c\ub3c4\uc5d0 \uc5c4\uaca9\ud788 \uc758\uc874\ud569\ub2c8\ub2e4. \uc804\ud1b5\uc801\uc778 \ud480\ub7ec\ub80c \ud569\uc131\uc740 <a href=\"https:\/\/www.thefullerene.com\/what-is-the-arc-discharge-method\/\" data-type=\"link\" data-id=\"https:\/\/www.thefullerene.com\/what-is-the-arc-discharge-method\/\">\ud0c4\uc18c \uc544\ud06c \ubc29\uc804\ubc95<\/a> \uc744 \ud1b5\ud574 \uc774\ub8e8\uc5b4\uc9c0\uba70, \ucd94\ucd9c \ubc0f \ubd84\ub9ac\ub97c \uc704\ud574 \ud1a8\ub8e8\uc5d4\uacfc \uac19\uc740 \uc720\uae30 \uc6a9\ub9e4\ub97c \uc790\uc8fc \uc0ac\uc6a9\ud569\ub2c8\ub2e4. \uc774\ub7ec\ud55c \ubc29\ud5a5\uc871 \ud0c4\ud654\uc218\uc18c\uc758 \ubbf8\ub7c9\uc774 \uc911\uacf5 \ud0c4\uc18c \ucf00\uc774\uc9c0 \ub0b4\uc5d0 \uac07\ud600 \uc788\uc73c\uba74 \uc2ec\uac01\ud55c \uc138\ud3ec \ub3c5\uc131\uc744 \uc720\ubc1c\ud558\uc5ec \uc0dd\ubb3c\ud559\uc801 \uc774\uc810\uc744 \uc0c1\uc1c4\uc2dc\ud0ac \uc218 \uc788\uc2b5\ub2c8\ub2e4.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\uc774\ub7ec\ud55c \uc548\uc804\uc131 \ubb38\uc81c\ub97c \ud574\uacb0\ud558\uae30 \uc704\ud574 \ud504\ub9ac\ubbf8\uc5c4 \uc2a4\ud0a8\ucf00\uc5b4 \uc6d0\ub8cc\ub294 \uc5c4\uaca9\ud55c \uc758\uc57d\ud488 \uae30\uc900 \ud558\uc5d0 \uc0dd\uc0b0\ub429\ub2c8\ub2e4. \uc0dd\uba85\uacf5\ud559 \uc120\ub3c4 \uae30\uc5c5\uc778 Healthyking\uc640 \ud611\ub825\ud558\ub294 \uc5c5\uacc4 \uc120\ub450\uc8fc\uc790 Carbonsphere\ub294 \uace0\uae09 <a href=\"https:\/\/www.thefullerene.com\/what-is-continuous-combustion-fullerene\/\">\uc5f0\uc18d \uc5f0\uc18c \uae30\uc220<\/a>. \uc744 \ud65c\uc6a9\ud569\ub2c8\ub2e4. \uc774 \uce5c\ud658\uacbd\uc801\uc774\uace0 \ubb34\uc6a9\ub9e4 \uc815\uc81c \uacf5\uc815\uc740 \ubaa8\ub4e0 \ud718\ubc1c\uc131 \uc720\uae30 \ud654\ud569\ubb3c\uc744 \uc81c\uac70\ud558\uc5ec \uc7a5\uae30\uac04 \uad6d\uc18c \uc0ac\uc6a9\uc5d0 \ub300\ud574 \uc644\uc804\ud788 \ubb34\ub3c5\uc131 \ubc0f \ubb34\uc790\uadf9\uc73c\ub85c \uc0dd\ubb3c\ud559\uc801\uc73c\ub85c \uac80\uc99d\ub41c \ucd08\uace0\uc21c\ub3c4(99.95%) \ud654\uc7a5\ud488 \ub4f1\uae09 C60 \uc131\ubd84\uc744 \uc0dd\uc0b0\ud569\ub2c8\ub2e4.<\/p>\n\n\n\n<h2 id=\"faq\" class=\"wp-block-heading\">FAQ<\/h2>\n\n\n\n<h3 id=\"how-does-c60-fullerene-differ-from-vitamin-c-as-a-skin-brightening-active\" class=\"wp-block-heading\">C60 \ud480\ub7ec\ub80c\uc740 \ud53c\ubd80 \ubbf8\ubc31 \ud65c\uc131 \uc131\ubd84\uc73c\ub85c\uc11c \ube44\ud0c0\ubbfc C\uc640 \uc5b4\ub5bb\uac8c \ub2e4\ub978\uac00\uc694?<\/h3>\n\n\n\n<p class=\"wp-block-paragraph\">\ube44\ud0c0\ubbfc C(L-\uc544\uc2a4\ucf54\ub974\ube0c\uc0b0)\ub294 \ud76c\uc0dd\uc801 \ud658\uc6d0\uc81c \uc5ed\ud560\uc744 \ud558\uba70, \uc774\ub294 \uc790\uc720 \ub77c\ub514\uce7c\uc744 \uc911\ud654\ud558\ub294 \uacfc\uc815\uc5d0\uc11c \uc18c\ube44\ub418\uace0 \uc0b0\ud654\ub41c\ub2e4\ub294 \uac83\uc744 \uc758\ubbf8\ud569\ub2c8\ub2e4.<sup><\/sup> \ub610\ud55c \ube5b, \uacf5\uae30 \ubc0f \uc5f4\uc5d0 \ub178\ucd9c\ub418\uba74 \ub9e4\uc6b0 \ubd88\uc548\uc815\ud558\uc5ec \ubd84\ud574\ub429\ub2c8\ub2e4. \ubc18\uba74, C60\uc740 \ub9e4\uc6b0 \uc548\uc815\uc801\uc778 \u201c\ub77c\ub514\uce7c \uc2a4\ud380\uc9c0\u201d\ub85c\uc11c \ubd84\ud574\ub418\uc9c0 \uc54a\uace0 \ucd09\ub9e4\uc801\uc73c\ub85c \uc5ec\ub7ec ROS \ubd84\uc790\ub97c \uc911\ud654\uc2dc\ud0a4\uba70, \ud53c\ubd80 \ub0b4\uc5d0\uc11c 24\uc2dc\uac04 \uc774\uc0c1 \uad11\uc548\uc815\uc131\uacfc \ud6a8\ub2a5\uc744 \uc720\uc9c0\ud569\ub2c8\ub2e4.<\/p>\n\n\n\n<h3 id=\"can-fullerenes-be-formulated-in-both-water-based-and-oil-based-cosmetics\" class=\"wp-block-heading\">\ud480\ub7ec\ub80c\uc740 \uc218\uc131 \ubc0f \uc720\uc131 \ud654\uc7a5\ud488 \ubaa8\ub450\uc5d0 \ubc30\ud569\ub420 \uc218 \uc788\uc2b5\ub2c8\uae4c?<\/h3>\n\n\n\n<p class=\"wp-block-paragraph\">\ub124. \uc21c\uc218 C60\uc740 \uc790\uc5f0\uc801\uc73c\ub85c \uc18c\uc218\uc131\uc774\ubbc0\ub85c \ud53c\uc9c0\uac00 \ud48d\ubd80\ud55c \uad6c\uc870\ub97c \ud45c\uc801\uc73c\ub85c \ud558\uace0 \uc138\ud3ec\ub9c9\uc744 \ubcf4\ud638\ud558\uae30 \uc704\ud574 \uc624\uc77c \uae30\ubc18 \uc81c\ud615(\uc608: \uc2dd\ubb3c \uc720\ub798 \uc2a4\ucfe0\uc54c\ub780)\uc5d0 \uc774\uc0c1\uc801\uc785\ub2c8\ub2e4. \uc138\ub7fc\uc774\ub098 \ud1a0\ub108\uc640 \uac19\uc740 \uc218\uc131 \uc81c\ud488\uc758 \uacbd\uc6b0, \uc81c\ud615 \uc804\ubb38\uac00\ub294 \uace0\ubd84\uc790 \ub7a9\ud551 \ubcf5\ud569\uccb4(PVP-\ub798\ud551 C60 \ub4f1) \ub610\ub294 \uace0\uc218\uc0b0\ud654 \uc218\uc6a9\uc131 \ud480\ub7ec\ub808\ub180(C60(OH)x)\uc744 \uc0ac\uc6a9\ud558\uba70, \uc774\ub294 \uc218\uc131\uc0c1\uc5d0 \uc27d\uac8c \ubd84\uc0b0\ub429\ub2c8\ub2e4.<\/p>\n\n\n\n<h3 id=\"does-c60-provide-actual-spf-protection-like-physical-sunscreens\" class=\"wp-block-heading\">C60\uc774 \ubb3c\ub9ac\uc801 \uc790\uc678\uc120 \ucc28\ub2e8\uc81c\uc640 \uac19\uc740 \uc2e4\uc81c SPF \ubcf4\ud638 \uae30\ub2a5\uc744 \uc81c\uacf5\ud569\ub2c8\uae4c?<\/h3>\n\n\n\n<p class=\"wp-block-paragraph\">\uc544\ub2c8\uc694, C60\uc740 \uc0b0\ud654\uc544\uc5f0\uc774\ub098 \uc774\uc0b0\ud654\ud2f0\ud0c0\ub284\uacfc \uac19\uc740 \ubb34\uae30 \uc790\uc678\uc120 \ucc28\ub2e8\uc81c\ub97c \ub300\uccb4\ud558\uc9c0 \uc54a\uc2b5\ub2c8\ub2e4. C60\uc740 \uad11\uc0b0\ub780 \ubc0f \uc77c\ubd80 UV \ud761\uc218 \ud2b9\uc131\uc744 \uac00\uc9c0\uace0 \uc788\uc9c0\ub9cc, \uc8fc\uc694 \uc5ed\ud560\uc740 \uc0dd\ubb3c\ud559\uc801 \uad11\ubcf4\ud638\uc785\ub2c8\ub2e4. \uc774\ub294 1\ucc28 \uc790\uc678\uc120 \ucc28\ub2e8\uc81c\ub97c \ud1b5\uacfc\ud55c UV \uad11\uc120\uc5d0 \uc758\ud574 \uc0dd\uc131\ub41c \uc5c4\uccad\ub09c \uc591\uc758 \ud65c\uc131\uc0b0\uc18c\uc885\uc744 \uc911\ud654\uc2dc\ucf1c \uc138\ud3ec \uad34\uc0ac\uc640 DNA \uc190\uc0c1\uc744 \ubc29\uc9c0\ud558\ub294 2\ucc28 \ubc29\uc5b4\ub9c9 \uc5ed\ud560\uc744 \ud569\ub2c8\ub2e4.<\/p>\n\n\n\n<h3 id=\"how-does-c60-prevent-uv-induced-dna-damage-in-skin-cells\" class=\"wp-block-heading\">C60\uc774 \ud53c\ubd80 \uc138\ud3ec\uc5d0\uc11c \uc790\uc678\uc120 \uc720\ubc1c DNA \uc190\uc0c1\uc744 \uc5b4\ub5bb\uac8c \uc608\ubc29\ud569\ub2c8\uae4c?<\/h3>\n\n\n\n<p class=\"wp-block-paragraph\">UVA \ubc0f UVB \ub178\ucd9c\uc740 DNA \uac00\ub2e5\uc744 \uacf5\uaca9\ud558\ub294 \uc138\ud3ec\ub0b4 \ucd08\uacfc\uc0b0\ud654\ubb3c\uacfc \uc218\uc0b0\uae30 \ub77c\ub514\uce7c\uc744 \uc0dd\uc131\ud569\ub2c8\ub2e4. \ud480\ub7ec\ub80c\uc740 \uc2e0\uc18d\ud558\uac8c \uac01\uc9c8\ud615\uc131\uc138\ud3ec \ub0b4\ub85c \ub4e4\uc5b4\uac00 \uc774\ub7ec\ud55c \uad6d\uc18c \ub77c\ub514\uce7c\uc744 \uc81c\uac70\ud558\uc5ec \uc5fc\uc0c9\uc9c8 \uc751\ucd95\uacfc \ud53c\ubd80\uc554\uc758 \uc8fc\uc694 \uc804\uad6c\uccb4\uc778 \uc0ac\uc774\ud074\ub85c\ubd80\ud0c4 \ud53c\ub9ac\ubbf8\ub518 \uc774\ub7c9\uccb4(CPD)\uc758 \ud615\uc131\uc744 \uc720\uc758\ubbf8\ud558\uac8c \uc5b5\uc81c\ud569\ub2c8\ub2e4.<\/p>\n\n\n\n<h3 id=\"are-there-any-side-effects-or-risks-associated-with-topical-c60\" class=\"wp-block-heading\">\uad6d\uc18c\uc6a9 C60\uacfc \uad00\ub828\ub41c \ubd80\uc791\uc6a9\uc774\ub098 \uc704\ud5d8\uc774 \uc788\uc2b5\ub2c8\uae4c?<\/h3>\n\n\n\n<p class=\"wp-block-paragraph\">\uc0dd\uccb4 \ub0b4 \ubc0f \uc2dc\ud5d8\uad00 \ub0b4 \ud53c\ubd80\uacfc\ud559\uc801 \uc548\uc804\uc131 \uc5f0\uad6c\uc5d0 \ub530\ub974\uba74 \uace0\uc21c\ub3c4 \ud654\uc7a5\ud488 \ub4f1\uae09 C60(\uc608: Carbonsphere \ubc0f Healthyking\uc5d0\uc11c \uc0dd\uc0b0\ub41c \uc2b9\ud654 \ubc0f \ubb34\uc6a9\ub9e4 \ub4f1\uae09)\uc740 \ud53c\ubd80 \uc790\uadf9, \uac10\uc791 \ub610\ub294 \uc720\uc804\ub3c5\uc131\uc744 \uc720\ubc1c\ud558\uc9c0 \uc54a\uc2b5\ub2c8\ub2e4. \uc8fc\uc694 \uc704\ud5d8\uc740 \uc794\ub958 \ud1a8\ub8e8\uc5d4 \uc6a9\ub9e4\ub97c \ud3ec\ud568\ud560 \uc218 \uc788\ub294 \uc800\ub4f1\uae09 \uc0b0\uc5c5\uc6a9 C60\uc5d0 \uc788\uc2b5\ub2c8\ub2e4.<sup><\/sup><\/p>\n\n\n\n<h2 id=\"references\" class=\"wp-block-heading\">\ucc38\uace0\ubb38\ud5cc<\/h2>\n\n\n\n<ol start=\"1\" class=\"wp-block-list\">\n<li>Xiao, L., Matsubayashi, K., &amp; Miwa, N. (2007). <em>\uc218\uc6a9\uc131 \uace0\ubd84\uc790 \ub7a9\ud551 \ud480\ub7ec\ub80c \uc720\ub3c4\uccb4\uac00 \uc778\uac04 \uba5c\ub77c\ub2cc\uc138\ud3ec \ubc0f \ud53c\ubd80 \uc870\uc9c1\uc5d0\uc11c \ud2f0\ub85c\uc2dc\ub098\uc81c \ubc1c\ud604 \ud558\ud5a5 \uc870\uc808\uc744 \ud1b5\ud574 UVA \uc720\ubc1c \uba5c\ub77c\ub2cc \uc0dd\uc131\uc5d0 \ubbf8\uce58\ub294 \uc5b5\uc81c \ud6a8\uacfc.<\/em> Archives of Dermatological Research, 299(5-6), 245-257. <a href=\"https:\/\/doi.org\/10.1007\/s00403-007-0740-2\" target=\"_blank\" rel=\"noreferrer noopener nofollow\">https:\/\/doi.org\/10.1007\/s00403-007-0740-2<\/a> \u201c<\/li>\n\n\n\n<li>Saitoh, Y., Miyanishi, A., Mizuno, H., Kato, S., Aoshima, H., Kokubo, K., &amp; Miwa, N. (2011). <em>\ucd08\uace0\uc218\uc0b0\ud654 \ud480\ub7ec\ub80c \uc720\ub3c4\uccb4\uac00 \uc138\ud3ec\ub0b4 ROS \uc0dd\uc131 \ubc0f DNA \uc190\uc0c1 \uac10\uc18c\uc640 \ud568\uaed8 UV \uc720\ubc1c \uc138\ud3ec \uc190\uc0c1\uc73c\ub85c\ubd80\ud130 \uc778\uac04 \uac01\uc9c8\ud615\uc131\uc138\ud3ec\ub97c \ubcf4\ud638\ud568.<\/em> Journal of Photochemistry and Photobiology B: Biology, 102(1), 69-76. <a href=\"https:\/\/doi.org\/10.1016\/j.jphotobiol.2010.09.006\" target=\"_blank\" rel=\"noreferrer noopener nofollow\">https:\/\/doi.org\/10.1016\/j.jphotobiol.2010.09.006<\/a> \u201c<\/li>\n\n\n\n<li>Aoshima, H., Yamana, S., Nakamura, S., &amp; Mashino, T. (2010). <em>\ud654\uc7a5\ud488 \ubc0f \uc758\uc57d\ud488 \uc81c\uc81c\uc5d0\uc11c \ud56d\uc0b0\ud654\uc81c\ub85c\uc11c \uc218\uc6a9\uc131 \uace0\ubd84\uc790 \ub7a9\ud551 \ud480\ub7ec\ub80c\uc758 \uc548\uc804\uc131 \ud3c9\uac00.<\/em> Journal of Toxicological Sciences, 35(3), 401-409. <a href=\"https:\/\/doi.org\/10.2131\/jts.35.401\" target=\"_blank\" rel=\"noreferrer noopener nofollow\">https:\/\/doi.org\/10.2131\/jts.35.401<\/a> \u201c<\/li>\n\n\n\n<li>Inui, S., Aoshima, H., Nishimori, A., &amp; Itami, S. (2011). <em>\uad6d\uc18c \ud480\ub7ec\ub80c \uc801\uc6a9\uc5d0 \uc758\ud55c \uc5ec\ub4dc\ub984 \uac1c\uc120.<\/em> Journal of Dermatology, 38(11), 1072-1077. <a href=\"https:\/\/doi.org\/10.1111\/j.1346-8138.2011.01257.x\" target=\"_blank\" rel=\"noreferrer noopener nofollow\">https:\/\/doi.org\/10.1111\/j.1346-8138.2011.01257.x<\/a> \u201c<\/li>\n\n\n\n<li>\ud654\uc7a5\ud488 \ub0b4 \ud480\ub7ec\ub80c \uc548\uc804\uc131 \ud3c9\uac00\uc5d0 \uad00\ud55c \ud45c\uc900\ud654\ub41c \uc9c0\uce68. (2023). \uc18c\ube44\uc790 \uc548\uc804 \uacfc\ud559 \uc704\uc6d0\ud68c(SCCS), \uc720\ub7fd\uc5f0\ud569 \uc9d1\ud589\uc704\uc6d0\ud68c. <a href=\"https:\/\/doi.org\/10.2772\/12171328\" target=\"_blank\" rel=\"noreferrer noopener nofollow\">https:\/\/doi.org\/10.2772\/12171328<\/a> \u201c<\/li>\n<\/ol>","protected":false},"excerpt":{"rendered":"<p>The cutaneous interface is constantly exposed to solar ultraviolet radiation (UVR), which is divided into UVB (290\u2013320 nm) and UVA (320\u2013400 nm) wavelengths. While UVB primarily targets the epidermis to cause direct DNA lesions, UVA penetrates deep into the dermis, generating an excess of reactive oxygen species (ROS). This UV-induced oxidative stress represents the primary [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":2400,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"_gspb_post_css":"","footnotes":""},"categories":[46],"tags":[],"class_list":["post-2394","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-technology"],"blocksy_meta":[],"acf":[],"_links":{"self":[{"href":"https:\/\/www.thefullerene.com\/ko\/wp-json\/wp\/v2\/posts\/2394","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.thefullerene.com\/ko\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.thefullerene.com\/ko\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.thefullerene.com\/ko\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.thefullerene.com\/ko\/wp-json\/wp\/v2\/comments?post=2394"}],"version-history":[{"count":0,"href":"https:\/\/www.thefullerene.com\/ko\/wp-json\/wp\/v2\/posts\/2394\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.thefullerene.com\/ko\/wp-json\/wp\/v2\/media\/2400"}],"wp:attachment":[{"href":"https:\/\/www.thefullerene.com\/ko\/wp-json\/wp\/v2\/media?parent=2394"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.thefullerene.com\/ko\/wp-json\/wp\/v2\/categories?post=2394"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.thefullerene.com\/ko\/wp-json\/wp\/v2\/tags?post=2394"}],"curies":[{"name":"\uc6cc\ub4dc\ud504\ub808\uc2a4","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}